In oncogenesis, a normal cell in our body is transformed and becomes a tumor cell, resulting in uncontrolled multiplication and impairment of central body functions. Mutations or errors in the translation of genetic information are among the causes of cancer formation, being held responsible for altering the genetic code.


At the Tyrolean Cancer Research Institute/Tiroler Krebsforschungsinstitut (TKFI), researchers with a wide range of expertise investigate the molecular causes of cancer aetiology and progression. The TKFI working groups from both Innsbruck Universities (Medizinische Universität Innsbruck (MUI) and Leopold-Franzens-Universität (LFU)) aim to understand the pathological effects of different cancer drivers and to uncover their mode of action at a molecular level. These teams strive to assist in identifying new approaches for personalized cancer therapies.

Who we are


Molecular Cancer

These projects focus on the molecular causes and progression of cancer.


Clinical Cancer

Projects involved emphasize cancer therapy and mechanisms of drug resistance.


Associated members

Associated projects deal with topics such as the analysis of respiratory gases, deciphering of oncoproteins, and establishment of organoids.

With your donation, you can support the Tyrolean cancer researchers!


Here we list for you news and scientific achievements chronologically.

Susan S. Taylor: New Frontiers in PKA Signaling

Susan S. Taylor, a distinguished Professor of Chemistry, Biochemistry and Pharmacology at the University of California, San Diego…

Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities

We are pleased to share news about a recently published TKFI paper by Jakob Fleischmann and his colleagues…

Sponsers & Partners

Special thanks go to our sponsors and partners for their great cooperation and support.