Publikationsliste
FOXO3/FKHRL1 is activated by 5-Aza-2-deoxycytidine (5-azadC) and induces silenced Caspase-8 in neuroblastoma.
Geiger, K.*, Hagenbuchner, J.*, Rupp, M., Fiegl, H., Sergi, C., Meister, B., Kiechl-Kohlendorfer, U., Müller, T., Ausserlechner, M.J.and Obexer, P.
1 Apr 2012; ().
FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.
Hagenbuchner J, Kuznetsov A, Hermann M, Hausott B, Obexer P, Ausserlechner MJ.
J Cell Sci. 20 Feb 2012; ().
Toll-like Receptor-9 expression in breast and ovarian cancer is associated with poorly differentiated tumors.
Berger, R., Fiegl, H., Goebel, G., Obexer, P., Ausserlechner, MJ., Doppler, W., Hauser-Kronberger, C., Reitsamer, R., Egle, D., Reimer, D., Müller-Holzner, E., Jones, A., Widschwendter, M.
Cancer Sci. 1 Apr 2010; 101(4)1059-66.
The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.
Hagenbuchner J, Ausserlechner MJ, Porto V, David R, Meister B, Bodner M, Villunger A, Geiger K, Obexer P.
J Biol Chem. 5 Mar 2010; 285(10)6904-12.
p16INK4A sensitizes human leukemia cells to FAS- and glucocorticoid-induced apoptosis via induction of BBC3/Puma and repression of MCL1 and BCL2
Obexer P, Hagenbuchner J, Rupp M, Salvador C, Holzner M, Deutsch M, Porto V, Kofler R, Unterkircher T, Ausserlechner MJ.
J Biol Chem. 6 Nov 2009; 284(45)30933-40.
Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis.
Obexer P, Hagenbuchner J, Unterkircher T, Sachsenmaier N, Seifarth C, Böck G, Porto V, Geiger K, Ausserlechner M.
Mol Biol Cell 1 May 2009; 20(7)2041-8.
Endothelial cells from cord blood CD133(+)CD34(+) progenitors share phenotypic, functional and gene expression profile similarities with lymphatics.
Nguyen VA, Fürhapter C, Obexer P, Stössel H, Romani N, Sepp N.
J Cell Mol Med. 9 Apr 2008; (). [Epub ahead of print]Click here to read
FKHRL1- mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells.
Obexer P, Geiger K, Ambros PF, Meister B, Ausserlechner MJ.
Cell Death Differ. 1 Mar 2007; 14(3)534-47.
A retroviral expression system based on tetracycline-regulated tricistronic transactivator/repressor vectors for functional analyses of antiproliferative and toxic genes.
Ausserlechner MJ, Obexer P, Deutschmann A, Geiger K, Kofler R.
Mol Cancer Ther. 1 Aug 2006; 5(8)1927-34.
G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression.
Ausserlechner MJ, Obexer P, Geley S, Kofler R.
Leukemia. 1 Jun 2005; 19(6)1051-7.
Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation.
Hainz U, Obexer P, Winkler C, Sedlmayr P, Takikawa O, Greinix H, Lawitschka A, Potschger U, Fuchs D, Ladisch S, Heitger A.
Blood. 15 May 2005; 105(10)4127-34. Epub 2005 Jan 27
Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells.
Ausserlechner MJ, Obexer P, Bock G, Geley S, Kofler R.
Cell Death Differ. 1 Feb 2004; 11(2)165-74.
Defective T-helper cell function after T-cell-depleting therapy affecting naive and memory populations.
Heitger A, Winklehner P, Obexer P, Eder J, Zelle-Rieser C, Kropshofer G, Thurnher M, Holter W.
Blood 1 Jun 2002; 99(11)4053-62.
The cell cycle inhibitor p16(INK4A) sensitizes lymphoblastic leukemia cells to apoptosis by physiologic glucocorticoid levels.
Ausserlechner MJ, Obexer P, Wiegers GJ, Hartmann BL, Geley S, Kofler R.
J Biol Chem. 15 Jun 2001; 276(24)10984-9.
Interaction of HSV-1 infected peripheral blood mononuclear cells with cultured dermal microvascular endothelial cells: a potential model for the pathogenesis of HSV-1 induced erythema multiforme.
Larcher C, Gasser A, Hattmannstorfer R, Obexer P, Fürhapter C, Fritsch P, Sepp N.
J Invest Dermatol. 1 Jan 2001; 116(1)150-6.
FOXO transcription factors as potential therapeutic targets in neuroblastoma
Ausserlechner, M. J., J. Hagenbuchner, S. Fuchs, K. Geiger, and P. Obexer.
In H. Shimada [ed.], Neuroblastoma - Present and Future ; ()325-348.
p16INK4A - connecting cell cycle control to cell death regulation in human leukemia, pp.
Obexer, P., J. Hagenbuchner, M. Holzner, and M. J. Ausserlechner
In O. Babusikova, S. Dovat, and K. S. Payne [eds.], T-cell Leukemia. ; ().
