Publikationsliste
FOXO3/FKHRL1 is activated by 5-Aza-2-deoxycytidine (5-azadC) and induces silenced Caspase-8 in neuroblastoma.
Geiger, K.*, Hagenbuchner, J.*, Rupp, M., Fiegl, H., Sergi, C., Meister, B., Kiechl-Kohlendorfer, U., Müller, T., Ausserlechner, M.J.and Obexer, P.
1 Apr 2012; ().
FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.
Hagenbuchner J, Kuznetsov A, Hermann M, Hausott B, Obexer P, Ausserlechner MJ.
J Cell Sci. 20 Feb 2012; ().
Toll-like Receptor-9 expression in breast and ovarian cancer is associated with poorly differentiated tumors.
Berger, R., Fiegl, H., Goebel, G., Obexer, P., Ausserlechner, MJ., Doppler, W., Hauser-Kronberger, C., Reitsamer, R., Egle, D., Reimer, D., Müller-Holzner, E., Jones, A., Widschwendter, M.
Cancer Sci. 1 Apr 2010; 101(4)1059-66.
The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.
Hagenbuchner J, Ausserlechner MJ, Porto V, David R, Meister B, Bodner M, Villunger A, Geiger K, Obexer P.
J Biol Chem. 5 Mar 2010; 285(10)6904-12.
The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway
Tominaga K, Tominaga E, Ausserlechner MJ, Pereira-Smith OM.
Exp Cell Res. 1 Jan 2010; 316(1)92-102.
p16INK4A sensitizes human leukemia cells to FAS- and glucocorticoid-induced apoptosis via induction of BBC3/Puma and repression of MCL1 and BCL2
Obexer P, Hagenbuchner J, Rupp M, Salvador C, Holzner M, Deutsch M, Porto V, Kofler R, Unterkircher T, Ausserlechner MJ.
J Biol Chem. 6 Nov 2009; 284(45)30933-40.
Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis.
Obexer P, Hagenbuchner J, Unterkircher T, Sachsenmaier N, Seifarth C, Böck G, Porto V, Geiger K, Ausserlechner M.
Mol Biol Cell 1 May 2009; 20(7)2041-8.
Premature aging of the immune system in children with juvenile idiopathic arthritis.
Prelog M, Schwarzenbrunner N, Sailer-Höck M, Kern H, Klein-Franke A, Ausserlechner MJ, Koppelstaetter C, Brunner A, Duftner C, Dejaco C, Strasak AM, Müller T, Zimmerhackl LB, Brunner J.
Arthritis Rheum. 1 Jul 2008; 58(7)2153-62.
Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation.
Spoden GA, Mazurek S, Morandell D, Bacher N, Ausserlechner MJ, Jansen-Dürr P, Eigenbrodt E, Zwerschke W.
Int J Cancer 18 Apr 2008; 123(2)312-321. [Epub ahead of print]
The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models.
Agu CA, Klein R, Schwab S, König-Schuster M, Kodajova P, Ausserlechner M, Binishofer B, Bläsi U, Salmons B, Günzburg WH, Hohenadl C.
J Gene Med. 1 Feb 2006; 8(2)229-41.
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.
Villunger A, Michalak EM, Coultas L, Müllauer F, Böck G, Ausserlechner MJ, Adams JM, Strasser A.
Science. 7 Nov 2003; 302(5647)1036-8.
Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.
Tonko M, Ausserlechner MJ, Bernhard D, Helmberg A, Kofler R.
FASEB J. 1 Mar 2001; 15(3)93-9.
FOXO transcription factors as potential therapeutic targets in neuroblastoma
Ausserlechner, M. J., J. Hagenbuchner, S. Fuchs, K. Geiger, and P. Obexer.
In H. Shimada [ed.], Neuroblastoma - Present and Future ; ()325-348.
p16INK4A - connecting cell cycle control to cell death regulation in human leukemia, pp.
Obexer, P., J. Hagenbuchner, M. Holzner, and M. J. Ausserlechner
In O. Babusikova, S. Dovat, and K. S. Payne [eds.], T-cell Leukemia. ; ().